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Articles (29)
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1

Distribution of Aβ peptide in whole blood

J. Randall Slemmon, Cory L. Painter, Sashi Nadanaciva, Florentina Catana, Ashley Cook, Ruth Motter, Peter Seubert

Journal:

Journal of Chromatography B

Année:

2007

Langue:

english

Fichier:

PDF, 182 KB

english, 2007

2

The molecular mechanism of ATP synthesis by F1F0-ATP synthase

Alan E. Senior, Sashi Nadanaciva, Joachim Weber

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2002

Langue:

english

Fichier:

PDF, 718 KB

english, 2002

3

Toxicity assessments of nonsteroidal anti-inflammatory drugs in isolated mitochondria, rat hepatocytes, and zebrafish show good concordance across chemical classes

Nadanaciva, Sashi, Aleo, Michael D., Strock, Christopher J., Stedman, Donald B., Wang, Huijun, Will, Yvonne

Journal:

Toxicology and Applied Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 356 KB

english, 2013

4

New Insights in Drug-Induced Mitochondrial Toxicity

Nadanaciva, Sashi, Will, Yvonne

Journal:

Current Pharmaceutical Design

Année:

2011

Langue:

english

Fichier:

PDF, 192 KB

english, 2011

5

Analysis of protein fragmentation inhibition by an MMP-inhibitor in an in vivo model of heart failure using automated chromatography

J. Randall Slemmon, Cory L. Painter, Sashi Nadanaciva, Florentina Catana, Karen Kaup, Rachel Scherrer, Virginia Casadas, Youyang Zhao, Marcia I. Heron

Journal:

Journal of Chromatography B

Année:

2005

Langue:

english

Fichier:

PDF, 208 KB

english, 2005

6

The Catalytic Transition State in ATP Synthase

Alan E. Senior, Joachim Weber, Sashi Nadanaciva

Journal:

Journal of Bioenergetics and Biomembranes

Année:

2000

Langue:

english

Fichier:

PDF, 329 KB

english, 2000

7

Lateral-flow immunoassay for detecting drug-induced inhibition of mitochondrial DNA replication and mtDNA-encoded protein synthesis

Sashi Nadanaciva, John H. Willis, Melissa L. Barker, Dima Gharaibeh, Roderick A. Capaldi, Michael F. Marusich, Yvonne Will

Journal:

Journal of Immunological Methods

Année:

2009

Langue:

english

Fichier:

PDF, 1021 KB

english, 2009

8

Mitochondrial impairment by PPAR agonists and statins identified via immunocaptured OXPHOS complex activities and respiration

Sashi Nadanaciva, James A. Dykens, Autumn Bernal, Roderick A. Capaldi, Yvonne Will

Journal:

Toxicology and Applied Pharmacology

Année:

2007

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2007

9

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

James A. Dykens, Joseph Jamieson, Lisa Marroquin, Sashi Nadanaciva, Puja A. Billis, Yvonne Will

Journal:

Toxicology and Applied Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2008

10

Target identification of drug induced mitochondrial toxicity using immunocapture based OXPHOS activity assays

Sashi Nadanaciva, Autumn Bernal, Robert Aggeler, Roderick Capaldi, Yvonne Will

Journal:

Toxicology in Vitro

Année:

2007

Langue:

english

Fichier:

PDF, 710 KB

english, 2007

11

Mitochondrial membrane potential measurement of H9c2 cells grown in high-glucose and galactose-containing media does not provide additional predictivity towards mitochondrial assessment

Payal Rana, Sashi Nadanaciva, Yvonne Will

Journal:

Toxicology in Vitro

Année:

2011

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2011

12

A high content screening assay for identifying lysosomotropic compounds

Sashi Nadanaciva, Shuyan Lu, David F. Gebhard, Bart A. Jessen, William D. Pennie, Yvonne Will

Journal:

Toxicology in Vitro

Année:

2011

Langue:

english

Fichier:

PDF, 846 KB

english, 2011

13

A pyrophosphate synthase gene: molecular cloning and sequencing of the cDNA encoding the inorganic pyrophosphate synthase from Rhodospirillum rubrum

Margareta Baltscheffsky, Sashi Nadanaciva, Anders Schultz

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

1998

Langue:

english

Fichier:

PDF, 459 KB

english, 1998

14

ATP-driven rotation of the γ subunit in F1-ATPase

Joachim Weber, Sashi Nadanaciva, Alan E Senior

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 203 KB

english, 2000

15

Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform

Sashi Nadanaciva, Payal Rana, Gyda C. Beeson, Denise Chen, David A. Ferrick, Craig C. Beeson, Yvonne Will

Journal:

Journal of Bioenergetics and Biomembranes

Année:

2012

Langue:

english

Fichier:

PDF, 485 KB

english, 2012

16

Mitochondrial bioenergetics and drug-induced toxicity in a panel of mouse embryonic fibroblasts with mitochondrial DNA single nucleotide polymorphisms

Claudia V. Pereira, Paulo J. Oliveira, Yvonne Will, Sashi Nadanaciva

Journal:

Toxicology and Applied Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2012

17

The contribution of oxidative stress to drug-induced organ toxicity and its detection in vitro and in vivo

Pereira, Claudia V, Nadanaciva, Sashi, Oliveira, Paulo J, Will, Yvonne

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2012

Langue:

english

Fichier:

PDF, 598 KB

english, 2012

18

A high-throughput dual parameter assay for assessing drug-induced mitochondrial dysfunction provides additional predictivity over two established mitochondrial toxicity assays

Hynes, James, Nadanaciva, Sashi, Swiss, Rachel, Carey, Conn, Kirwan, Sinead, Will, Yvonne

Journal:

Toxicology in Vitro

Année:

2013

Langue:

english

Fichier:

PDF, 531 KB

english, 2013

19

Validation of a HTS-amenable assay to detect drug-induced mitochondrial toxicity in the absence and presence of cell death

Swiss, Rachel, Niles, Andrew, Cali, James J., Nadanaciva, Sashi, Will, Yvonne

Journal:

Toxicology in Vitro

Année:

2013

Langue:

english

Fichier:

PDF, 470 KB

english, 2013

20

High throughput glutathione and Nrf2 assays to assess chemical and biological reactivity of cysteine-reactive compounds

Naven, Russell T., Kantesaria, Sheila, Nadanaciva, Sashi, Schroeter, Thomas, Leach, Karen L.

Journal:

Toxicology Research

Année:

2013

Langue:

english

Fichier:

PDF, 988 KB

english, 2013

21

New Probes of the F 1 -ATPase Catalytic Transition State Reveal That Two of the Three Catalytic Sites Can Assume a Transition State Conformation Simultaneously †

Nadanaciva, Sashi, Weber, Joachim, Senior, Alan E.

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 84 KB

english, 2000

22

The Role of β-Arg-182, an Essential Catalytic Site Residue in Escherichia coli F 1 -ATPase

Nadanaciva, Sashi, Weber, Joachim, Senior, Alan E.

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 100 KB

english, 1999

23

Importance of F 1 -ATPase Residue α-Arg-376 for Catalytic Transition State Stabilization †

Nadanaciva, Sashi, Weber, Joachim, Wilke-Mounts, Susan, Senior, Alan E.

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 170 KB

english, 1999

24

Investigating Mitochondrial Dysfunction to Increase Drug Safety in the Pharmaceutical Industry

Nadanaciva, Sashi, Will, Yvonne

Journal:

Current Drug Targets

Année:

2011

Langue:

english

Fichier:

PDF, 150 KB

english, 2011

25

Development of a cell viability assay to assess drug metabolite structure–toxicity relationships

Rana, Payal, Will, Yvonne, Nadanaciva, Sashi, Jones, Lyn H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2016

Langue:

english

Fichier:

PDF, 346 KB

english, 2016

26

The αβ dimer - catalytic unit of the F 1 -ATPase

BENZ, SABINE, NADANACIVA, SASHI, HARRIS, DAVID

Journal:

Biochemical Society Transactions

Année:

1995

Langue:

english

Fichier:

PDF, 117 KB

english, 1995

27

Impact of a planned dose interruption of dacomitinib in the treatment of advanced non-small-cell lung cancer (ARCHER 1042)

Kim, Dong-Wan, Garon, Edward B., Jatoi, Aminah, Keefe, Dorothy M., Lacouture, Mario E., Sonis, Stephen, Gernhardt, Diana, Wang, Tao, Giri, Nagdeep, Doherty, Jim P., Nadanaciva, Sashi, O’Connell, Josep

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 540 KB

english, 2017

28

Interstitial Lung Disease Associated With Crizotinib in Patients With Advanced Non–Small Cell Lung Cancer: Independent Review of Four PROFILE Trials

Yoneda, Ken Y., Scranton, Judith R., Cadogan, Michael A., Tassell, Vanessa, Nadanaciva, Sashi, Wilner, Keith D., Stollenwerk, Nicholas S.

Journal:

Clinical Lung Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2017

29

Prediction of metabolism-induced hepatotoxicity on three-dimensional hepatic cell culture and enzyme microarrays

Yu, Kyeong-Nam, Nadanaciva, Sashi, Rana, Payal, Lee, Dong Woo, Ku, Bosung, Roth, Alexander D., Dordick, Jonathan S., Will, Yvonne, Lee, Moo-Yeal

Journal:

Archives of Toxicology

Année:

2017

Langue:

english

Fichier:

PDF, 4.40 MB

english, 2017